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Enhancement of solubility of Mebendazole by SEDDS by Aparna Lanka, Naveen Patel (Paperback, 2012)

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Publisher: LAP Lambert Academic Publishing. Format: Paperback. Item Length: 152mm. Item Weight: 163g. Country/Region of Manufacture: DE. Item Height: 229mm. ISBN-10: 3659116335. Language: English.

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The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for increasing its solubility. Various oils, surfactants and co-surfactants were screened for their suitability in the formulation of SEDDS. Based on the initial screening, Omix of Tocopherol acetate and Peceol in the ratio 6:4 and surfactant, Labrasol and co-surfactant, PEG 200 were found to be satisfactory. Five formulations were selected from pseudoternary phase diagrams and were evaluated for parameters like drug content, percentage transmittance, dilution potential, centrifugation test, in-vitro release study, emulsification time and dispersibility, emulsion droplet size, zeta potential, polydispersibility index and ex-vivo permeation studies. All the formulations exhibited a rapid emulsification rate and a good polydispersibity index. The size of the droplets as determined by zeta sizer was found to be below 300 nm. The percentage drug release from the formulations was improved compared to that of pure drug. Thus, the formulated SEDDS helped in improving the solubility and dissolution of the drug, thereby increasing its therapeutic effectiveness.

Product Identifiers

Publisher
Lap Lambert Academic Publishing
ISBN-13
9783659116339
eBay Product ID (ePID)
138724075

Product Key Features

Author
Aparna Lanka, Naveen Patel
Publication Name
Enhancement of Solubility of Mebendazole by Sedds
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2012
Type
Textbook
Number of Pages
104 Pages

Dimensions

Item Height
229mm
Item Width
152mm
Item Weight
163g

Additional Product Features

Title_Author
Aparna Lanka, Naveen Patel
Country/Region of Manufacture
Germany

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item 1 Naveen Patel Aparna L Enhancement of solubility of Mebendazole by S (Paperback)
AU $130.06
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item 2 Naveen Patel Ap Enhancement of solubility of Mebendazol (Paperback) (US IMPORT)
AU $131.60
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Enhancement of solubility of Mebendazole by SEDDS by Aparna Lanka, Naveen Patel (Paperback, 2012)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

All listings for this product

item 1 Naveen Patel Aparna L Enhancement of solubility of Mebendazole by S (Paperback)

item 2 Naveen Patel Ap Enhancement of solubility of Mebendazol (Paperback) (US IMPORT)

Best Selling in Adult Learning & University

A guide to the Project Management Body of Knowledge (PMBOK guide) and the Standard for project management by Project Management Institute (Paperback, 2021)

The Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by Adam Grubb, Annie Raser-Rowland (2012, Paperback)

Polyvagal Exercises for Safety and Connection: 50 Client-Centered Practices by Deb Dana (Paperback, 2020)

Save on Adult Learning & University

Ford Falcon EF, EL/Fairlane NF, NL/LTD DF, DL 1994-1998 Haynes Workshop Manual

Netter Atlas of Human Anatomy: Classic Regional Approach

Michael Price Nick Vandome Windows 11 for Seniors in easy steps (Paperback)

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The Demon-Haunted World: Science as a Candle in the Dark by Carl Sagan (English)

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