This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
Product Identifiers
Publisher
Springer London Ltd
ISBN-13
9781447153092
eBay Product ID (ePID)
189437240
Product Key Features
Author
Florian Frommlet, Malgorzata Bogdan, David Ramsey
Publication Name
Phenotypes and Genotypes: the Search for Influential Genes
Format
Hardcover
Language
English
Subject
Medicine, Engineering & Technology, Biology, Mathematics, Healthcare System
Publication Year
2016
Type
Textbook
Number of Pages
222 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Volume
18
Item Weight
4794g
Additional Product Features
Title_Author
David Ramsey, Florian Frommlet, Malgorzata Bogdan
Series Title
Computational Biology
Country/Region of Manufacture
United Kingdom
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