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A Handbook for DNA-encoded Chemistry: Theory and Applications for Exploring Chemical Space and Drug Discovery by Robert A. Goodnow (Hardback, 2014)

This book comprehensively describes the development and practice of DNA-encoded library synthesis techlogy. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation techlogies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen vel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available chemical space for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry techlogy and methods

Place of Publication
New York
Spine
32mm
Content Note
Illustrations
Author Biography
ROBERT A. GOODNOW, J. is the Executive Director of the Chemistry Innovation Centre, Discovery Sciences at AstraZeneca and the Founder of GoodChem Consulting, LLC. He has extensive experience in drug discovery and chemistry technologies including carbohydrate, combinatorial, oligonucleotide, and analytical chemistry. Robert Goodnow has authored or coauthored nearly 100 publications and patents and has spoken extensively on the topics of drug lead finding and the outsourcing of drug discovery chemistry. He has lectured as an adjunct professor of medicinal chemistry.
Date of Publication
08/08/2014
Country of Publication
United States
Genre
Chemistry

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