Picture 1 of 1

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 8Human Diseases by M. A. Hayat (Hardcover, 2016)

Be the first towrite a review.

simplybestprices-10to20dayshipping (471079)
98.2% positive Feedback

Price:

AU $292.00

Free postage

Estimated delivery Tue, 18 Jun - Mon, 15 Jul

Returns:

30-day returns. Buyer pays for return postage.

Condition:

Brand new

Autophagy plays a key role in the anticancer response to Chemotherapy. However, autophagy can increase or decrease the effectiveness of chemotherapy. The reasons for these contradictory effects are explained.

About this product

Product Information

Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections. Volume 8 Autophagy and Human Diseases, concentrates on the role of Autophagy in human diseases, including tumorigenesis. The diseases discussed include melanoma, liver cancer, pancreatic cancer, and neurodegenerative disorders. Loss of autophagy in the central nervous system causes neurodegeneration (Alzheimers disease, Huntington's disease, Parkin's disease, and Amyotrophic Lateral Sclerosis). Melanoma is one of the most serious diseases in humans. Autophagy plays a key role in the anticancer response to Chemotherapy. However, autophagy can increase or decrease the effectiveness of chemotherapy. The reasons for these contradictory effects are explained. Autophagy also plays a role in idiopathic inflammatory diseases, infection, and immunity. An explanation is given how autophagy is closely linked to control of innate and adaptive immune responses in host defense in part by regulating cytokine production. The role of autophagy in cutaneous malignant melanoma is discussed in detail and expression of Beclin 1 and LC3 autophagic genes in melanoma is included to explain the molecular mechanisms underlying this very serious disease, which tends to metastasize to the brain. The effect of the treatment of this disease using Terfenadine through the induction of autophagy and apoptosis is also included. Autophagy and apoptosis are two main mechanisms involved in programmed cell death. Considering that autophagy is associated with numerous biological processes including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases, there is a great need to understanding its role. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological situations (conditions) mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood. Volumes in the Series Volume 1: Molecular Mechanisms. Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and executi

Product Identifiers

Publisher
Elsevier Science Publishing Co Inc
ISBN-13
9780128029374
eBay Product ID (ePID)
220734546

Product Key Features

Author
M. A. Hayat
Publication Name
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 8Human Diseases
Format
Hardcover
Language
English
Subject
Medicine, Biology
Publication Year
2016
Type
Textbook
Number of Pages
418 Pages

Dimensions

Item Height
235mm
Item Width
191mm
Item Weight
970g

Additional Product Features

Country/Region of Manufacture
United States
Editor
M. A. Hayat

No ratings or reviews yet.No ratings or reviews yet.

Be the first to write a review.

Best Selling in Adult Learning & University

See all

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Best Selling in Adult Learning & University

Permaculture: A Designer's Manual by Bill Mollison (Hardcover, 1988)
5.0 out of 5 stars based on 12 product ratings
AU $182.95 New
---- Used
1871-2021 History Debunked: How Wars and the Scapegoat for Zionism Were Created by Rowald Holt (Paperback, 2020)
5.0 out of 5 stars based on 1 product rating
AU $39.80 New
---- Used
Doug Stone's Gold Atlas of Victoria by Douglas M. Stone (Spiral Bound, 2011)
4.8 out of 5 stars based on 21 product ratings
AU $117.00 New
AU $100.00 Used
Australian Native Bee Book: Keeping Stingless Bee Hives for Pets, Pollination and Sugarbag Honey by Tim Heard (Paperback, 2015)
4.9 out of 5 stars based on 157 product ratings
AU $44.98 New
AU $31.50 Used
The Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by Adam Grubb, Annie Raser-Rowland (2012, Paperback)
4.8 out of 5 stars based on 88 product ratings
AU $19.95 New
AU $13.00 Used
Australian Master Bookkeepers Guide - 8th Edition by Stephen J Marsden (Paperback, 2020)
No ratings or reviews yet.
AU $126.45 New
---- Used
Sapiens: A Brief History of Humankind by Yuval Noah Harari (Paperback, 2015)
4.8 out of 5 stars based on 57 product ratings
AU $19.57 New
AU $14.62 Used

Save on Adult Learning & University

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Save on Adult Learning & University

Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by A
AU $19.95
Trending at AU $20.57
Essential Enrolled Nursing Skills for Person-Centred Care WorkBook
AU $49.95
Trending at AU $66.45
The Ethnic Cleansing of Palestine by Ilan Pappe (English) Paperback Book
AU $23.99
Trending at AU $31.31
Ford Falcon EF EL / Fairlane NF NL 1994 - 1998 Workshop Manual
AU $49.00
Trending at AU $59.16
The Red Book: Liber Novus by Carl Gustav Jung (English) Hardcover Book
AU $322.59
Trending at AU $394.18
George Hrabovsky Leonard Susskind Classical Mechanics (Paperback)
AU $27.60
Trending at AU $31.47

Shop by category

Picture 1 of 1

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 8Human Diseases by M. A. Hayat (Hardcover, 2016)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Permaculture: A Designer's Manual by Bill Mollison (Hardcover, 1988)

1871-2021 History Debunked: How Wars and the Scapegoat for Zionism Were Created by Rowald Holt (Paperback, 2020)

Doug Stone's Gold Atlas of Victoria by Douglas M. Stone (Spiral Bound, 2011)

Australian Native Bee Book: Keeping Stingless Bee Hives for Pets, Pollination and Sugarbag Honey by Tim Heard (Paperback, 2015)

The Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by Adam Grubb, Annie Raser-Rowland (2012, Paperback)

Australian Master Bookkeepers Guide - 8th Edition by Stephen J Marsden (Paperback, 2020)

Sapiens: A Brief History of Humankind by Yuval Noah Harari (Paperback, 2015)

Save on Adult Learning & University

Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by A

Essential Enrolled Nursing Skills for Person-Centred Care WorkBook

The Ethnic Cleansing of Palestine by Ilan Pappe (English) Paperback Book

Ford Falcon EF EL / Fairlane NF NL 1994 - 1998 Workshop Manual

The Red Book: Liber Novus by Carl Gustav Jung (English) Hardcover Book

George Hrabovsky Leonard Susskind Classical Mechanics (Paperback)

You may also like

Non-Fiction Diseases Hardcover Books

Hardcovers Comic Book Single Volume

Hardcovers Comic Book Single Volume in English

Aging Non-Fiction Hardcover Books

Non-Fiction Diseases Paperback Fiction & Books

Non-Fiction Coming of Age Hardcover Books