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G Protein-coupled Receptors: Molecular Pharmacology by Georges Vauquelin, Bengt von Mentzer (Hardcover, 2007)

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Product Information

G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly. G Protein-coupled Receptors: Molecular Pharmacology provides a clear summary of the current knowledge in this fast-evolving field. The book sets out with an introduction to signalling molecules and their receptors, and an overview of the technical approaches used to investigate these interactions. Structural, functional and especially pharmacological aspects of GPCRs are then discussed in more detail and much attention is devoted to the analysis and interpretation of experimental data. The now widespread use of recombinant cell lies, receptor mutants and related artifices in drug research is critically evaluated. Special attention is also devoted to topical but often poorly understood concepts, such as insurmountable antagonism, inverse agonism and allosteric interactions. By combining general information with the major state-of-the-art concepts in GPCR-research, this outstanding book equips the reader with the necessary background for understanding and critically evaluating the current literature. Written by two experts from academia and industry, G Protein-coupled Receptors: Molecular Pharmacology offers a unique view of academic and applied approaches aiming to reveal new ideas in pharmaceutical research. The book is of interest to anyone involved in drug development and preclinical research and those who need to function within multi-disciplinary teams in the pharmaceutical industry: from investigators to product managers or clinicians who seek to have a broad mechanistic understanding of drug-receptor interactions. It is also an invaluable resource for final year undergraduate and postgraduate students in pharmacology and cell and molecular biology.

Product Identifiers

Publisher
John Wiley & Sons Inc
ISBN-13
9780470516478
eBay Product ID (ePID)
94755978

Product Key Features

Subject Area
Chemical Engineering
Author
Georges Vauquelin, Bengt Von Mentzer
Publication Name
G Protein-Coupled Receptors: Molecular Pharmacology
Format
Hardcover
Language
English
Publication Year
2007
Type
Textbook
Number of Pages
264 Pages

Dimensions

Item Height
246mm
Item Width
174mm
Item Weight
698g

Additional Product Features

Title_Author
Bengt Von Mentzer, Georges Vauquelin
Country/Region of Manufacture
United States

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G Protein-coupled Receptors: Molecular Pharmacology by Georges Vauquelin, Bengt von Mentzer (Hardcover, 2007)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Maps of Meaning: The Architecture of Belief by Jordan B. Peterson (1999, Paperback)

Eduqas GCSE (9-1) Religious Studies Route B: Catholic Christianity and Judaism by Deirdre Cleary, Andrew Barron, Joy White, Patrick Harrison (Paperback, 2017)

Aradale: The Making of a Haunted Asylum by Nathaniel Buchanan, David Waldron, Sharn Waldron (Paperback, 2020)

Silent Spring by Rachel Carson (Paperback, 2000)

Understanding and Treating Chronic Shame: Healing Right Brain Relational Trauma by Patricia A. DeYoung (Paperback, 2021)

Time Management by Peter Quarry (Paperback, 1986)

Save on Adult Learning & University

The Australian Native Bee Hive Book: Keeping Stingless Sugarbag OATH Tim Heard

Netter Atlas of Human Anatomy: Classic Regional Approach

Havard's Nursing Guide to Drugs

George Hrabovsky Leonard Susskind Classical Mechanics (Paperback)

Robert A. Monroe Journeys Out of the Body (Paperback) Journeys Trilogy

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