For those of us who have labored in the field of hormonal carcigenesis, it has been most gratifying to see its rapid growth and increasing relevance in recent years. Although many factors and forces have contributed to this phemen, a few appear particularly significant. Perhaps foremost is the realization that two of the most prevalent cancers which afflict women and men; that is, breast and prostate, have essential hormonal component(s) to their etiologies. This should t surprise us since the high frequency of these cancers in human populations has to date t been attributed to any exogeus physical, environmental, or dietary factor(s). A similar argument may be applied to other less prevalent but equally important cancers including ovarian, endometrial, testicular, cervico- vaginal, pituitary, thyroid, and sex hormone-associated hepatic neoplasms. The Office of Research on Women's Health and many women's interest groups have been instrumental in fostering research and public awareness on women's cancers. Similar concern is beginning to emerge for solely male cancers by other groups. To illustrate an example of the potential pervasive role of hormones in the human, particularly sex hormones, Figure I depicts the endogeus and kwn exogeus exposures to estrogens and progestins during a woman's lifetime, which may contribute to increased risk for hormonally-associated cancers . . = iii M. A. P. _ GI en 2 PoOlmepauoal ~ EstrogDn ~ Proge. tln GI en J\ Ovulatory _ 2 Cyel. iii W DES EIP Metr . 1 Ol,order.
Product Identifiers
Publisher
Springer-Verlag New York Inc.
ISBN-10
1461275067
ISBN-13
9781461275060
eBay Product ID (ePID)
189241275
Product Key Features
Format
Paperback
Language
English
Subject
Clinical Medicine: Professional
Dimensions
Weight
831g
Height
235mm
Width
155mm
Additional Product Features
Place of Publication
New York, NY
Spine
28mm
Edited by
Satyabrata Nandi, Sara A. Li, Lea I. Sekely, Jonathan J. Li, Jan-Ake Gustafsson