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About this product
- DescriptionSince the pioneering discoveries of Hodgkin, Huxley, and Katz, it has been clear that specific ion conductance pathways underlie electrical act- ity. Over the ensuing 50 years, there has been ever increasing, and occasi- ally explosive, changes in the scope of efforts to understand ion channel behavior. The introduction of patch clamp techlogy by Erwin Neher and Bert Sakmann about 20 years ago led to the realization of the great variety of vel ion channel species, and the subsequent revolution in cl- ing has revealed an even greater diversity of the underlying molecular entities. Today, advances in the study of ion channel structure and function c- tinue at a high pace, from angstrom resolution imaging of crystallized ch- nels to their genetic manipulations in animals. In this regard, the field is a balanced one that inquires t only what ion channel entities are there, or how they operate, but also where are these molecular electronic switches? However, this balance is t particularly well presented to the general sci- tific audience or to specialists in the field. There are plenty of wonderful and useful books and mographs, as well as conferences and meetings on v- tually every aspect of ion channel structure and function. However, we are unaware that the channel localization theme has been considered in a u- fied forum.
- PublisherHumana Press Inc.
- Date of Publication28/10/2010
- SubjectClinical Medicine: Professional
- Series TitleMethods in Pharmacology and Toxicology
- Place of PublicationTotowa, NJ
- Country of PublicationUnited States
- ImprintHumana Press Inc.
- Content Notebiography
- Weight760 g
- Width152 mm
- Height229 mm
- Spine26 mm
- Edited byAnatoli Lopatin,Colin G. Nichols
- Format DetailsTrade paperback (US)
- Edition Statement1st ed. Softcover of orig. ed. 2001
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