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Modulation of MHC Antigen Expression and Disease by Cambridge University Press (Paperback, 2005)
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item 1 - Modulation of MHC Antigen Expression and Disease (2005, Paperback)
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About this product
Description
- DescriptionThe major histocompatibility complex (MHC) genes are involved in the immune system's response to tumour and infected cells and in generating an immune response. This book brings together basic aspects of the regulation of MHC antigens with important clinical applications (in viral infection, viral oncology, cancer biology and autoimmunity). There is a strong emphasis on situations where MHC expression is modulated (either stimulated or repressed). The book's major themes are: the mechanisms of MHC expression explored at several levels including the transcription and translation of MHC genes and the insertion of MHC protein molecules into plasma membranes; the effect of cytokines on MHC expression both in the aetiology of certain diseases and in possible immutherapeutic approaches to disease; and the use of gene therapy to modify MHC expression in cancer cells, and thereby cause tumour rejection.
Key Features
- PublisherCambridge University Press
- Date of Publication03/11/2005
- LanguageEnglish
- FormatPaperback
- ISBN-100521499216
- ISBN-139780521499217
- SubjectLife Sciences: General
Publication Data
- Place of PublicationCambridge
- Country of PublicationUnited Kingdom
- ImprintCambridge University Press
- Content Note47 b/w illus. 22 tables
Dimensions
- Weight640 g
- Width152 mm
- Height228 mm
- Spine24 mm
Credits
- Edited byCraig R. Pringle,D. John Maudsley,G. Eric Blair
Editorial Details
- Format DetailsTrade paperback (US)
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