It is an age when monsters rule the world, soaring through the sky, treading the earth and filling the seas. Humanity survives on the fringes, relying on a special kind of hero to defend the people from danger - the Monster Hunters! Together with his fellow Hunters, Raiga continues to hunt in various lands. When they receive a request from Moga Village to subdue a Lagiacrus, Raiga's party heads out on the quest, but a Rathalos descends upon the same hunting ground. For humans to oppose monsters is a reckless act, yet there are those who push the limits of what is possible. How will the party handle a simultaneous hunt for the King of the Skies and the Lord of the Seas?