Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases by Akhlaq A. Farooqui (Hardback, 2010)

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This type of cell death leads to membrane lysis and release of intracellular components that induce inflammatory reactions. Necrotic cell death normally occurs at the core of injury site. In contrast, apoptosis is an active process in which caspases (a group of endoproteases with specificity for aspartate residues in protein) are stimulated.