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- DescriptionIt can be concluded (under the specific experimental procedures em- ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did t differ sig- nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport- ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is t concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intraveus injection; 6) There are four different phases of ovarian uptake of HCG, namely:- the first phase, when there is only an inflow from the circulation and stor- age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in- flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.
- PublisherSpringer-Verlag New York Inc.
- Date of Publication07/12/2013
- SubjectLife Sciences: General
- Series TitleAdvances in Experimental Medicine and Biology
- Series Part/Volume Number2
- Place of PublicationNew York
- Country of PublicationUnited States
- ImprintSpringer-Verlag New York Inc.
- Content Notebiography
- Weight1267 g
- Width178 mm
- Height254 mm
- Spine35 mm
- Edited byNathan Back
- Edition StatementSoftcover reprint of the original 1st ed. 1968
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