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Physiology of Astroglia: Channels, Receptors, Transporters, Ion Signaling and Gliotransmission by Vladimir Parpura, Alexei Verkhratsky (Paperback, 2015)

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Astrocytes can be defined as the glia inhabiting the nervous system with the main function in the maintenance of nervous tissue homeostasis. Classified into several types according to their morphological appearance, many of astrocytes form a reticular structure known as astroglial syncytium, owing to their coupling via intercellular channels organized into gap junctions. Not only do astrocytes establish such homocellular contacts, but they also engage in intimate heterocellular interactions with neurons, most notably at synaptic sites. As synaptic structures house the very core of information transfer and processing in the nervous system, astroglial perisynaptic positioning assures that these glial cells can nourish neurons and establish bidirectional communication with them, functions outlined in the concepts of the astrocytic cradle and multi-partite synapse, respectively. Astrocytes possess a rich assortment of ligand receptors, ion and water channels, and ion and ligand transporters, which collectively contribute to astrocytic control of homeostasis and excitability. Astroglia control glutamate and adenosine homeostasis to exert modulatory actions affecting the real-time operation of synapses. Fluctuations of intracellular calcium can lead to the release of various chemical transmitters from astrocytes through a process termed gliotransmission. Sodium fluctuations are closely associated to those of calcium with both dynamic events interfacing signaling and metabolism. Astrocytes appear fully integrated into the brain cellular circuitry, being an indispensable part of neural networks.

Product Identifiers

Publisher
Morgan & Claypool Publishers
ISBN-13
9781615046720
eBay Product ID (ePID)
214431187

Product Key Features

Author
Vladimir Parpura, Alexei Verkhratsky
Publication Name
Physiology of Astroglia: Channels, Receptors, Transporters, Ion Signaling and Gliotransmission
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2015
Type
Textbook
Number of Pages
172 Pages

Dimensions

Item Height
235mm
Item Width
191mm
Item Weight
333g

Additional Product Features

Title_Author
Vladimir Parpura, Alexei Verkhratsky
Series Title
Colloquium Series on Neuroglia in Biology and Medicine: from Physiology to Disease
Country/Region of Manufacture
United States

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Physiology of Astroglia: Channels, Receptors, Transporters, Ion Signaling and Gliotransmission by Vladimir Parpura, Alexei Verkhratsky (Paperback, 2015)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Eduqas GCSE (9-1) Religious Studies Route B: Catholic Christianity and Judaism by Deirdre Cleary, Andrew Barron, Joy White, Patrick Harrison (Paperback, 2017)

Australian Guidebook for Structural Engineers by Lonnie Pack (Paperback, 2019)

Taking Charge of Adult ADHD by Christine M. Benton, Russell A. Barkley (Paperback, 2021)

Time Management by Peter Quarry (Paperback, 1986)

Save on Adult Learning & University

Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by A

Netter Atlas of Human Anatomy: Classic Regional Approach

Havard's Nursing Guide to Drugs

Classical Mechanics: The Theoretical Minimum by George Hrabovsky

NEW Learn to Earn By Peter Lynch Paperback Free Shipping

Steven Holzner Physics Essentials For Dummies (Paperback)

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