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Proteases, Protease Inhibitors and Protease-Derived Peptides: Importance in Human Pathophysiology and Therapeutics by Repine, J. Cheronis (Paperback, 2012)

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Product Information

Proteases, Protease-Derived Peptides and Protease Inhibitors Many physiological as weil as pathophysiological processes are mediated by proteases and the products of their actions, protease-derived peptides. However, the uncontrolled activity of proteases can be extraordinarily destructive and dangerous to normal biologie systems. As a result, biology has gone to great lengths to control the activities of the proteases involved in these systems by developing aseries of both highly specific (regulatory) and non-specific (protective) anti-proteases. The protease/anti-protease balancing activities include the normal homeostatic processes of clotting and clot lysis, hormonal regulation of blood pressure and the control of the inflammatory response represented by both the humoral (the kallikrein-kinin and complement systems) and cellular (neutrophil and macrophage derived proteases) components of the inflammation. Examples of successful therapies directed at these protease dependent systems include the use of warfarin and heparin to control thrombosis and streptokinase or tissue plasminogen activator (tPA) for the acceleration of clot dissolution. Similarly, the use of angiotensin converting enzyme (ACE, a type of limited activity protease or peptidase) inhibitors has made a significant impact on the treatment of hypertension. Lastly, the restitution of normal antiprotease levels by the infusion of the purified protein in patients with genetic alpha-1-antiprotease deficiency is regularly being used to reduce the rate of lung function 1055 caused by the unopposed activity of human neutrophil elastase in these individuals.

Product Identifiers

Publisher
Springer Basel
ISBN-13
9783034873994
eBay Product ID (ePID)
190288565

Product Key Features

Author
Repine, J. Cheronis
Publication Name
Proteases, Protease Inhibitors and Protease-Derived Peptides: Importance in Human Pathophysiology and Therapeutics
Format
Paperback
Language
English
Subject
Education
Publication Year
2012
Type
Study Guide
Number of Pages
248 Pages

Dimensions

Item Height
244mm
Item Width
170mm
Volume
42
Item Weight
455g

Additional Product Features

Title_Author
J. Cheronis, Repine
Series Title
Agents and Actions Supplements
Country/Region of Manufacture
Switzerland

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Proteases, Protease Inhibitors and Protease-Derived Peptides: Importance in Human Pathophysiology and Therapeutics by Repine, J. Cheronis (Paperback, 2012)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in School Textbooks & Study Guides

Tracks, Scats and Other Traces: Reissue by Barbara Triggs (Paperback, 2004)

Save on School Textbooks & Study Guides

Excel Success One HSC Mathematics Extension 1 2024 Edition

Powerless: Tiktok Made Me Buy It! an Epic and Sizzling Fantasy Romance Not

Targeting Mental Maths Australian Curriculum Year 5 - New Edition 2023

Medication Log Book: Simple Personal Medication Administration Planner & Record

Bindi: Winner of the Daisy Utemorrah Award by Kirli Saunders (Paperback) FREE Sh

The Meateater Fish and Game Cookbook: Recipes and Techniques for Every Hunter an

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