Nowadays, life expectancy is two times higher than in the beginning of the 20th century, therefore, the human body is subjected to higher cumulative stress that results in degradation of the tissues and so new therapies are required to overcome these problems. Thus, a new biomaterial was developed, a modified apatite with silicon, as it is well known silicon plays an important role on several metabolic pathways. Hence, this book describes the in vitro characterization of Silicon-Hydroxyapatite developed to enhance bone regeneration. The studies described in this book show the role of Silicon-Hydroxyapatite on several physical, chemical and biological processes. The results indicate that the enhanced bioactivity of Silicon-Hydroxyapatite is a combination of acellular and cellular mechanisms. The more negative surface and higher dissolution rate decreases the time required for the formation of an apatite layer, which is considered to be an important factor for osseointegration. And also the enhanced proliferation and differentiation of bone cells (human osteoblast and osteoclast) induced by the presence of Silicon-Hydroxyapatite can lead to faster bone regeneration.
Product Identifiers
Publisher
Lap Lambert Academic Publishing
ISBN-13
9783845404295
eBay Product ID (ePID)
109215129
Product Key Features
Author
Claudia Botelho
Publication Name
Silicon-Substituted Hydroxyapatite
Format
Paperback
Language
English
Subject
Biology
Publication Year
2011
Type
Textbook
Number of Pages
200 Pages
Dimensions
Item Height
229mm
Item Width
152mm
Item Weight
299g
Additional Product Features
Title_Author
Claudia Botelho
Country/Region of Manufacture
Germany
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