Advances in polymeric biomaterials allow the emergent of the field of Regenerative Medicine which gave hope to many patients around the world. The shortage in organ donation, the immunoreactions to allotransplants, and the high cost associated with transplantation are some reasons for the growing interest in Tissue Engineering. This work focuses on the material selection and processing which are keys for a successful design of any tissue engineered structure. Poly(L-lysine) (PLL) was selected in this work as a base for developing scaffolds due to its biocombatability and bioabsorbability. PLL, however, has limitations in use due to its hydrophilicity that weakens its structures in aqueous and physiological conditions. To overcome these limitations, two hypotheses were studied in this work; the first hypothesis is that a micro-scale composite of PLL with a high crystalline material can enhance the final properties of PLL. The second hypothesis is that; properties of PLL structures can be controlled by forming a molecular-scale composite with another crosslinked bioresorbable polymer. Molecular Modeling techniques were also implemented in this study.
Product Identifiers
Publisher
Lap Lambert Academic Publishing
ISBN-13
9783846535455
eBay Product ID (ePID)
190483844
Product Key Features
Subject Area
Bioengineering, Chemical Engineering
Author
Mohamed Farag a Eldessouki
Publication Name
Synthesis and Modeling of Poly (L-Lysine) Based Biomaterials
Format
Paperback
Language
English
Publication Year
2011
Type
Textbook
Number of Pages
160 Pages
Dimensions
Item Height
229mm
Item Width
152mm
Item Weight
245g
Additional Product Features
Title_Author
Mohamed Farag a Eldessouki
Country/Region of Manufacture
Germany
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