After losing her job and learning that her husband has been unfaithful, a woman hits the road with her profane, hard-drinking grandmother.
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Allison Janney, Ben Falcone, Dakota Lee, Dan Aykroyd, Gary Cole, Kathy Bates, Mark Duplass, Melissa McCarthy, Nat Faxon, Rich Williams, Sandra Oh, Sarah Baker, Steve Little, Susan Sarandon, Toni Collette