As we approach the twenty-first century the problems of industrialization are evident: we find there is a greenhouse effect, the ozone layer is being depleted, the rain is acidified, and there is a terrible problem of increasing C0 concentrations in the atmo 2 sphere. The carbonic anhydrases are a unique family of enzymes that solve these problems in the human body: they are responsible for converting C0 (a gas) to 2 HC0-, which is the biggest intracellular buffer, with a concomitant decrease in a 3 hydroxyl ion. Globally, the functions of the carbonic anhydrases in photosynthesis in rain forests and in the algae and plankton that cover our oceans indicate that they are also of utmost importance in the maintenance of the acid-base balance on our planet. Although the whole field of C0 metabolism is enormous and still rapidly 2 expanding, because of the research interests of the editors this book is mainly concerned with mammalian carbonic anhydrases. However, if the interested reader intends to purify carbonic anhydrases from nonmammalian sources, Dr. Cheg widden has provided the necessary information in Chapter 7. The carbonic anhydrases were first discovered in 1933; until1976 there were thought to be only two isozymes. Since then CA ill, IY, V, VI, and Vll have been discovered and well characterized. There is, of course, no reason to believe that we have found them all.
Product Identifiers
Publisher
Springer Science+Business Media
ISBN-13
9780306436369
eBay Product ID (ePID)
96068563
Product Key Features
Author
S.J. Dodgson, G. Gros, N.D. Carter, R.E. Tashian
Publication Name
The Carbonic Anhydrases: Cellular Physiology and Molecular Genetics
Format
Hardcover
Language
English
Subject
Chemistry, Zoology, Physics
Publication Year
1991
Type
Textbook
Number of Pages
380 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Item Weight
1670g
Additional Product Features
Country/Region of Manufacture
United States
Editor
G. Gros, N.D. Carter, R.E. Tashian, S.J. Dodgson
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