The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.
Product Identifiers
Publisher
Morgan & Claypool Publishers
ISBN-13
9781615041381
eBay Product ID (ePID)
106627625
Product Key Features
Author
Stephen J. Pandol
Publication Name
The Exocrine Pancreas
Format
Paperback
Language
English
Subject
Medicine, Psychiatry
Publication Year
2011
Type
Textbook
Number of Pages
64 Pages
Dimensions
Item Height
235mm
Item Width
191mm
Item Weight
147g
Additional Product Features
Title_Author
Stephen J. Pandol
Series Title
Colloquium Series on Integrated Systems Physiology
Country/Region of Manufacture
United States
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