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The Macrophage as Therapeutic Target by Siamon Gordon (Hardcover, 2003)

About this product

About this product

Product Information

During the past decade, the rapid growth of molecular and cellular knowledge of macrophages, as a specialized host defense and homeostatic system, has begun to offer attractive targets for therapeutic intervention. Macrophages play a central role in a wide range of disease processes, from genetically determined lysosomal storage diseases, to acute sepsis, chronic inflammation and repair, tissue injury and cell death. Under- or overactivity of macrophage clearance, immune effector functions and responses to metabolic abnormalities contribute to common disorders such as autoimmunity, atherosclerosis, Alzheimers disease and major infections including AIDS and Tuberculosis. Whilst the goals of therapeutic intervention based on improved understanding of macrophage functions and their contribution to pathogenesis may seem self evident, there are considerable difficulties in producing useful new agents. The present volume covers a range of subjects and provides opportunities for a more focused macrophage-targeted approach. The individual chapters review selected topics briefly, to place cellular processes and molecular targets in perspective. Overall, the volume should provide a broad sample of the state of the art. Useful reviews and references in the literature are cited within individual chapters.

Product Identifiers

Publisher
Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
ISBN-13
9783540442509
eBay Product ID (ePID)
95898342

Product Key Features

Author
Siamon Gordon
Publication Name
The Macrophage As Therapeutic Target
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2003
Type
Textbook
Number of Pages
496 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Volume
158
Item Weight
1015g

Additional Product Features

Series Title
Handbook of Experimental Pharmacology
Editor
Siamon Gordon
Country/Region of Manufacture
Germany

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