Abstract: Schistosomiasis remains one of the most prevalent parasitic diseases in the sub-Saharan Africa including Ethiopia where Schistosoma mansoni and Schistosoma hematobium are widespread. praziquantel has been the most effective drug and used as mass chemotherapy. However, recently low cure rate recorded in different parts of the word. As it is the only drug used for schistosomiasis, there is a need to periodically evaluate the efficacy in different geographic settings. So this study evaluateed efficacy of Praziquantel against S.mansoni. Cross-sectional study was conducted in Fincha Valley followed by non randomized trial. Positive students treated with praziquantel 40mg/kg. Cure and reduction rate evaluated 4 weeks after treatment through fecal egg count by two Kato - Katz on two consecutive days. Data was analyzed and parasitological cure rate and egg reduction rate was 80.9% & 99.5% respectively. There was a significant association between cure rate and pre-treatment infection intensity (P > 0.05), but not between cure rate and age groups (P
Product Identifiers
Publisher
Lap Lambert Academic Publishing
ISBN-13
9783845472959
eBay Product ID (ePID)
190415766
Product Key Features
Author
Samuel Haile
Publication Name
Therapeutic Efficacy of Praziquantel Against Schistosoma Mansoni