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Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk by F.J. De Serres (Paperback, 2011)

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The magnitude of the threat to the human genetic material posed by environmental agents has t as yet been fully determined. Never- theless, the potential hazards of many chemicals have been identi- fied by studies on lower organisms. However, too little is kwn regarding the comparability or lack of it between the metabolic pathways available in such organisms and those in man. Although at present there is great public concern for what is considered by some as the excessive use of laboratory animals in toxicological testing, it seems clear that the usage of mammalian systems may be deemed necessary. It has been proposed that cell culture systems might suffice to meet this need, however, such approaches cant match the complexity of physiological occurances that are present in the intact animal. For studies of genetic effects, some n-invasive human test systems are presently available. These do t, however, meet the re- quirements for extensive laboratory studies. In order to assess the risks to humans of environmental factors such laboratory investiga- tions are essential. Therefore, for the forseeable future reliance on experiments using laboratory animals will be necessary. This Volume, which contains the proceedings of a workshop which was held at the National Institute of Environmental Health Sciences, March 29-31, 1982, explores the existing methodologies and their utility for risk estimations. It covers the most well developed human systems, as well as the most widely used animal tests.

Product Identifiers

Publisher
Springer-Verlag New York Inc.
ISBN-10
1461337410
ISBN-13
9781461337416
eBay Product ID (ePID)
189255341

Product Key Features

Author
F.J. De Serres
Format
Paperback
Language
English
Subject
Physics
Type
Textbook

Dimensions

Weight
607g
Height
244mm
Width
170mm

Additional Product Features

Place of Publication
New York, NY
Spine
19mm
Series Part/Volume Number
28
Series Title
Environmental Science Research
Content Note
Biography
Date of Publication
13/10/2011
Genre
Physics
Country of Publication
United States

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Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk by F.J. De Serres (Paperback, 2011)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Permaculture: A Designer's Manual by Bill Mollison (Hardcover, 1988)

Australian Native Bee Book: Keeping Stingless Bee Hives for Pets, Pollination and Sugarbag Honey by Tim Heard (Paperback, 2015)

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