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Yeast as a Tool in Cancer Research by Joseph Heitman, John L Nitiss (Hardcover, 2007)

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About this product

Product Information

Leland H. Hartwell Director, Fred Hutchinson Cancer Research Center, Nobel Laureate for Medicine, 2001 Yeast has proved to be the most useful single-celled organism for studying the fundamental aspects of cell biology. Resources are now available for yeast that greatly simplify and empower new investigations, like the presence of strains with each gene deleted, each protein tagged and databases on protein-protein interactions, gene regulation, and subcellular protein location. A powerful combination of genetics, cell biology, and biochemistry employed by thousands of yeast researchers has unraveled the complexities of numerous cellular processes from mitosis to secretion and even uncovered new insights into prion diseases and the role of prions in normal biology. These insights have proven, time and again, to foretell the roles of proteins and pathways in human cells. The collection of articles in this volume explores the use of yeast in pathway analysis and drug discovery. Yeast has, of course, supplied mankind's most ubiquitous drug for thousands of years. In one aspect, the role of yeast in drug discovery is much like the role of yeast in other areas of biology. Yeast offers the power of genetics and a repetoire of resources available in no other organism. Using yeast in the study of drug targets and metabolism can help to make a science of what has been largely an empirical activity. A science of drug discovery would permit rigorous answers to important questions.

Product Identifiers

Publisher
Springer-Verlag New York Inc.
ISBN-13
9781402059629
eBay Product ID (ePID)
94726883

Product Key Features

Subject Area
Bioengineering
Author
Joseph Heitman, John L Nitiss
Publication Name
Yeast As a Tool in Cancer Research
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2007
Type
Textbook
Number of Pages
433 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Item Weight
840g

Additional Product Features

Country/Region of Manufacture
United States
Editor
John L Nitiss, Joseph Heitman

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